Olink® Proteomics
Protein analysis services using Olink technology
Our service portfolio includes high throughput protein analysis utilizing cutting-edge Olink® Proximity Extension Assay. Considered a next-gen proteomics platform, Olink technology enables unparalleled throughput and specificity (Figure 1). Its consistent and reliable results have made it widely recognized and extensively cited in various research fields for protein profiling and biomarker development.
Figure 1. Protein measurement with Olink proximity extension assay (PEA) technology. (A) Samples are mixed with paired antibodies labeled with complementary DNA oligonucleotides. When the antibody pair correctly binds to its target protein in solution, the oligonucleotides hybridize to each other. (B) The hybridized oligonucleotides are amplified via PCR and analyzed with next-generation sequencing or qPCR. (C) No DNA amplicons are generated if nonspecific binding occurs.
Target
18 different panels. Up to 88 samples, and up to 92 markers of interest per panel.
Flex | Focus
Personalized panel creation, 5-30 markers from a library selection of up to 5400 proteins across 40 samples.
Reveal
Enables the measurement of up to 1,000 robustly detectable protein biomarkers, offering broad proteome coverage and deep insights into inflammation processes
Proximity Extension Assay
How it works:
IMCO was an early adopter.
Onboarding Olink®’s technology and their flagship instrument, the Q100, and one of the first labs to certify as a service provider.