Bioinformatics & Research Analytics Services

Complex multi-omics datasets become actionable biological insights through integrated bioinformatics, statistical analysis, biomarker discovery, and data visualization services. IMCO supports Olink proteomics, CycIF spatial biology, Mass cytometry, genomics, and translational research programs with end-to-end analytical expertise.

Click here to download our sample report!

Radar chart illustrating immune cell populations, including CD8+ T cells, Tregs, Th1-like cells, CD20+ B cells, granulocytes, DCs, macrophages, and other APCs, with data series labeled PR in green, SD in yellow, and PD in pink.
An orange abstract graphic resembling connected circles or molecules on a black background.

Spatial Biology & Cyclic ImmunoFluorescence Analysis

Transform high-dimensional spatial imaging datasets into biologically meaningful insights through cell segmentation, spatial phenotyping, neighborhood analysis, tissue architecture mapping, and tumor microenvironment characterization.

Bar graph showing cell densities for major immune populations before and after drug treatment. Categories include Cytoffe, mIHC, with cell densities measured in cells per mm².
Microscopic view with three arrows pointing to small, irregularly shaped green structures against a dark background.
Scatter plot showing a positive correlation between two variables, labeled 'Pearson Correlation' with axes labeled 'CGB Curve' (x-axis) and 'CGB Line' (y-axis).
A heatmap displaying immune cell types across different patient IDs and timepoints, with color coding from red to blue indicating variations in data values.
Bar graph showing percentages of different B cell types across multiple patients and samples. The B cell types are Ki67+, PD1+, PDL1+, CD69+, CD103+, and CD39+.
A scatter plot showing various types of immune cells, including circulating monocytes, macrophages, resident macrophages, T cells, and unclassified cells, distinguished by different colors. The plot has labeled axes for X and Y in millimeters.

Biomarker Validation

Have a novel antibody or target you need to validate? IMCO provides an end-to-end pipeline, from wet lab optimization through quantitative correlation analysis. By benchmarking your candidate against gold standard assays with rigorous positive and negative controls, we ensure your biomarker delivers a signal that stands above the noise — giving you the confidence to move forward.

Microscopic image showing cells stained with a pink dye, with three black arrows pointing to specific cell structures.

Exploratory Immune Profiling & Contexture Analysis

Starting with tissue samples and an undefined omic profile? We'll help you find your footing. IMCO delivers a comprehensive quantitative breakdown of the immune and cellular contexture of each sample, revealing hidden relationships and patterns across your dataset. Think of us as your research compass — orienting your findings, generating meaningful hypotheses, and empowering you to ask the right questions.

Bar chart titled 'Cell Densities for Major Immune Populations' showing cell densities across 17 samples, with color-coded segments for different immune cell types including CD8+ T Cells, Tregs, Th1-like Cells, Th2-like Cells, Unconventional T Cells, B Cells, Macrophages, Monocytes, and Dendritic Cells.
Circular chart comparing Mac and Monos segments with color-coded subcategories including CD163, TIm3+, and Mac, showing percentages for each segment.

Clinical Cohort & Biomarker Analysis

For clinical trials or studies with well-defined research questions, IMCO offers rigorous cohort analysis tailored to your specific objectives. From longitudinal tracking across timepoints to responder vs. non-responder comparisons and multi-arm therapeutic evaluations, we deliver publication-ready visualizations, robust statistics, and spatial analysis. The result: clear, defensible evidence to support confident, data-driven decisions.

Clients receive:

  • QC reports

  • Statistical analysis summaries

  • Heatmaps

  • Volcano plots

  • PCA and UMAP visualizations

  • Differential expression analyses

  • Pathway enrichment reports

  • Publication-ready figures

  • Consultation and interpretation support

IMCO supports analysis of:

  • Olink proteomics

  • CycIF spatial biology

  • Mass cytometry (CyTOF)

  • Multiplex immunohistochemistry

  • RNA sequencing

  • Whole exome sequencing

  • Digital spatial profiling

  • Multi-omics datasets

Line graph showing major immune populations' cell density before and after a stimulus or event, with increased diversity and cell density post-event, and a legend mapping colors to immune cell types.
Box plot comparing macrophage cell density at three time points: Archival, Pre, and On, with scatter points indicating measurements above and below median PFS.

Deliverables

Supported Data Types